Paxil As We Know It Today - Health Article

By:Nick Johnson

Released in 1992 by the GlaxoSmithKline pharmaceutical company, Paxil has become well known for its effectiveness in treating depression, obsessive compulsive disorders and various other anxiety disorders or phobias.

In some western hemisphere countries, including the United States, Paxil (and Paxil CR) is the trade name for paroxetine. Paxil is considered to be one of the newer antidepressant medications. These newer medications have fewer side effects than older antidepressant drugs, and the side effects that do occur, are better handled by the individuals taking such medications. Paxil has been approved by the Food and Drug Administration (FDA) to treat obsessive-compulsive disorder (OCD) as well as panic disorders. Physicians have also legally prescribed Paxil for other ailments such as bulimia, premenstrual syndrome, alcohol and nicotine addiction.

Known as selective serotonin-specific reuptake inhibitors (SSRIs), these drugs are currently the most frequently prescribed antidepressant medications. Often referred to as a chemical imbalance by lay people, medical studies note that depression can be caused by an imbalance of the serotonin system in the brain.

Nerve cells in the brain communicate with each other by passing messages through small gaps between the cells - synapse. The cells sending information release neurotransmitters. One such neurotransmitter is known as serotonin. If the released serotonin is accepted by the recipient cell, there is communication between the cells and messages are forwarded. However, some serotonin is lost in the process while other returns to the sending cell. SSRIs inhibit the reuptake of serotonin that is initially released, thereby increasing the level of serotonin available to facilitate cell to cell communication.

Based on the premise that depression is associated with a lack of stimulation of the recipient neuron at a synapse, to stimulate the recipient cell, SSRIs inhibit the reuptake of serotonin. By prescribing an SSRI medication such as Paxil, the reuptake of the serotonin is inhibited, thus allowing the neurotransmitter to remain in the synaptic gap longer than it normally would. This allows the receptor cell the opportunity to recognize serotonin over and over again with the expectation that recognition will occur and the recipient cell will then be fully stimulated.

SSRIs affect only the reuptake pumps responsible for serotonin, versus older antidepressants, which affect other neurotransmitters as well. Because of this, SSRIs are described as 'selective' and lack some of the side effects of the earlier drugs.

Before SSRIs were developed, more commonly prescribed antidepressant medications were known as tricyclic antidepressant, sometimes referred to as TCA. The effectiveness between the TCA medications versus SSRIs seems to be insignificant. However SSRIs have a high toxic dose which makes them less dangerous if a patient were contemplating suicide. Some general side effects caused by SSRIs are: nausea, headache, anxiety, restlenssness or trouble sleeping. Studies suggest that SSRIs such as Paxil may promote the growth of new neural pathways. Also, SSRIs may protect against neurotoxicity caused by other compounds as well as from depression itself.

Paxil prescription in North America has only been approved for patients 18 years of age or older.

On Dec 13, 2006, a U.S. Food and Drug Administration advisory panel recommended that black-box warnings on SSRIs be raised from 18 to 25 years old. Although the FDA is not obliged to follow the recommendations of its advisory committees, it generally does.

Digg del.icio.us Blink Stumble Spurl Reddit Netscape Furl

Article keywords: paxil, attorney, Houston, birth defects, Texas

Article Source: http://www.articles2k.com

Nick Johnson serves as lead counsel with Johnson Law Group, with principal offices located in Houston, Texas. Johnson represents plaintiffs with injury cases involving Defective Drugs. Contact Nick Johnson at 1-888-311-5522 or visit http://www.johnsonlawgroup.com

Top Health Articles
1). Collarbone Injury By : Frank Vanderlugt The clavicle or “collar bone” connects the scapula bone in the shoulder to the sternum in your chest. It functions to hold the shoulder upward and backward. Clavicle fractures are common bone injuries. A break in the clavicle bone is usually a closed fracture that normally takes approximately 6 weeks to heal in an adult, 4 weeks in a child. The injury rarely requires surgery.
2). The Hottest Hair Trends And The Sexiest Hairstyles For 2007 By : Copyright 2006 David Maillie Hair has become unequivocally important as it can literally make one look like a movie star or a has been from Hee Haw, which died out many years ago. It is big enough that it is a multi billion dollar industry and the average bill in a salon is approaching $100. In the big cities with a hot hairstylist like Jonathon in Beverly Hills prices can easily top $500 for a cut and style.
3). Muscle Imbalance And Chronic Injuries By : Jeff P. Anliker, LMT Injuries can occur anywhere and at anytime, but the most prevalent place of occurrence is in the workplace. The reason for such a high rate of injury is that people spend 8-18 hours a day, 5-7 days a week performing unidirectional (one-way) movement patterns, causing an imbalance in the musculoskeletal system that results in the overuse and under use of certain muscle groups.
4). Why Whey Protein? By : Sandy Knoll With all of the recent negative press given to body supplements, it makes good sense to be cautions about using different nutritional supplements as a part of your body building efforts. Whey protein has been lauded as a safe, natural and simple supplement. It's use has become popular for those genuinely interested in good health through physical fitness and body building.
5). Autism and its Generated Behavioral and Mental Impairments By : Groshan Fabiola Autism is a complex neurological disorder that dramatically affects people’s behaviors and social interactions. The disorder can be revealed in early childhood, by the age of 3. Although the first signs of autism can sometimes be identified in infants, the disorder is usually discovered at a later stage of life. Autistic children present a wide range of behavioral abnormalities, and they can be easily identified among normal children.
6). Why Asbestos Cancer Affects More Men? By : Alfred J.James Who needs to be examined? Individuals who have been exposed (or suspect they have been exposed) to asbestos fibers on the job or at home via a family contact should inform their physician of their exposure history and any symptoms. Asbestos fibers can be measured in urine, feces, mucus, or material rinsed out of the lungs. A thorough physical examination, including a chest x-ray and lung function tests, may be recommended.
7). The Benefits of Martial Arts Training By : Clint Leung As any martial arts practitioner will tell you, there are multiple benefits in martial arts training. Of course, the most obvious benefit is a knowledge of self defense which is one of the major reasons why the martial arts were developed in the first place. Knowing how to defend oneself and loved ones in a potentially dangerous situation is an asset in today’s world just as it was hundreds of years ago.
8). Study Says Obesity May Be Caused By Virus By : Rick Hendershot In new study published this month, a research team claims to have found evidence that a contagious virus can contribute to obesity. The team found that a specific human adenovirus Ad-37 seems to trigger obesity in chickens. Previous studies had linked other adenoviruses -- Ad-36 and Ad-5 -- to obesity in animals. These and other adenoviruses cause colds and other common illnesses in people.
9). How Long Will It Take To Gain Muscles\| Build Muscle Mass By : Chris Chew There are many factors to consider when you want to know how long will it take for you to gain and build muscle mass. Questions like are you eating enough and the right nutrients to accelerate muscle growth, are you exercising correctly and regularly and do you have the genes for quick muscle growth need to be addressed. In this article, we shall discuss whether you have the genetic make up to gain and build muscles quickly.
10). Breathe Easy: Some Asthma Relief Tips By : Nick Carter Asthma is the seventh-ranked chronic health condition in the United States and the leading chronic illness of children. It is a chronic inflammatory disease that makes airways (bronchial tubes) particularly sensitive to irritants. During an asthma attack, tightening of the smooth muscles around the bronchial tubes causes them to become inflamed, narrow inside, and produce excess mucus.

New Health Articles
1). How To Break An Addiction By : John Morris You need to evaluate the problem and find what triggers your addicts and what specific need it is using. Once you have determined that, you can begin breaking yourself of the habit one step at a time...
2). How Disabled People Overcome Their Disabilities For Better Sexual Health By : Gregg Hall For the most part these people can participate in sexual activity and take pleasure in the intimacy of having a partner. Participating in a healthy sexual relationship is a critical part of therapy do the disabled and helps them rebuild self confidence.
3). Fight Those Winter Time Blues ! By : ian Williamson In North America, it is estimated that 50 to 60 percent of the population is affected by winter depression.
4). Cord Blood Banking: A Medical Safety Net By : Greg Roy Why pregnant women should consider cord blood banking when their children are born.
5). Make Your Heart More Healthy By : Dan Sherman Does it seem like there are more health risks these days than there were in the past? Well, the plain and simple truth is, there are. Now, more than ever, people around the globe grapple with various heath afflictions.
6). The Best Ways To Quit Cigarette Smoking By : Jonty Smith The author packed in his 40-a-day habit within a few hours. He did it quickly, easily and painlessly. Why then do so many other smokers struggle to quit? In this article, the author explains the best ways to quit cigarette smoking, and why many of the established methods are counter-productive.
7). Can Chocolate Really Kill Your Dog By : Gregg Hall We have all heard this all of our lives but how big a threat is it really? Is it life threatening or will it just make him sick? How much chocolate does the animal have to eat for it to cause a negative reaction?
8). The Attraction Of Magnetic Therapy By : John Morris Magnetic therapy is an alternative treatment for common ailments. The most commonly treated ailments for that magnetic therapy is used for are arthritis, pain, inflammation, muscle tension, migraines, tumors, asthma, allergies, diabetes and many other joints or healing complaints...
9). Symptoms, Signs, and Triggers of Anxiety Attacks By : Amit Mehta Discover key symptoms and signs of anxiety attacks, and how they affect the lives of anxiety attack sufferers. Also, learn how an anxiety attack can be coupled with agoraphobia, the fear of open spaces.
10). Power Scooters...Ask The Right Questions To Get The Right Answers By : RC Rougeux Asking the right questions can help you find out the information important to you. Use these when shopping for your next power scooter.