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Aaron Hall Profile and Articles
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251). JGI Informatics: Tracking a Moving Target
Providing informatics support for achieving "dream" targets of 100 Mb a year of Bermuda-quality sequence is an evolving process, said Tom Slezak, director of the JGI informatics team. "It can't happen in a single leap. It will ride a learning curve similar to all the other scientific and technological ones going on in parallel," he said. But a lag time for informatics support on these processes is inevitable because support requirements are not yet clear.
252). ACEDB Version 4.0 Debuts at Annual Meeting
Since its 1991 introduction for the Caenorhabditis elegans community, ACEDB has served as a data-management model for other research projects and has been adopted by a number of diverse organizations and individuals to maintain and distribute data on more than 40 genomes, including human, bovine, Drosophila, yeast, mycobacteria, Arabidopsis, grains, trees, and fungi.
253). Mouse Resources Critical to Understanding Human Genome
Some 60 scientists met for 3 days in March 1998 in Bethesda, Maryland, to define priorities for producing resources to make the mouse a more valuable tool for understanding mammalian biology. Convened by NIH Director Harold Varmus, the Mouse Genomics and Genetics Resources Working Group's recommendations, as summarized by cochairs William Dove (University of Wisconsin) and David Cox (Stanford University), are outlined below.
254). Drosophila Researchers Win Prize
At its annual meeting in San Francisco on February 17, the American Association for the Advancement of Science presented the prestigious Newcomb Cleveland Prize to five researchers representing the teams that completed the sequence of the fruit fly. Gerald Rubin and Susan Celniker accepted the prize on behalf of the Berkeley Drosophila Genome Project (BDGP), and J.
255). Public, Private Sectors Join in Mouse Consortium
Sequencing Results will Spur Discovery of Human Genes and Their Functions
In October, a collaboration was announced to speed up sequencing of the mouse genome and produce a draft map by spring 2001. The Mouse Sequencing Consortium (MSC) consists of six NIH institutes, the Wellcome Trust philanthropy, and three private companies. It provides another example of public and private sectors joining forces to support large-scale genomics research and generate freely available data crucial for basic biomedical research.
256). Genetic Testing Advisory Committee
The Secretary's Advisory Committee on Genetic Testing (SACGT) of the Department of Health and Human Services (DHHS) held its first meeting in June. Chaired by Edward McCabe (University of California, Los Angeles), the 13-member committee's task is to help DHHS formulate policies on the development, validation, and regulation of genetic tests, particularly DNA-based diagnostics.
257). Congressional Hearing Explores Controversies, Benefits of Genomics
In April the Subcommittee on Energy and Environment of the Committee on Science of the U.S. House of Representatives conducted hearings on the status and benefits of genome sequencing in the public and private sectors. Speakers included representatives of the U.S. HGP and Celera Genomics, members of Congress, and the director of the Office of Science and Technology Policy.
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